@article{Tarashoki_Azizi_Pelarak_Kermani_Madmoli_Khodadadi_Najarian_2019, title={The Effect of Hypericum Perforatum L. on Severity of Early Menopause Symptoms}, volume={10}, url={https://www.ijam.co.in/index.php/ijam/article/view/1274}, DOI={10.47552/ijam.v10i2.1274}, abstractNote={<p>Objective: Menopause might lead to physical, mental problems for women and also disruption theirlife quality. Despite the existance of a single treatment to remove the disorders, herbal medicine is referable to chemical one in that they alleviate the related symptoms. The present research study aims to investigate the effect of <em>Hypericum Perforatum</em> L. on severity of early symptoms of menopause. Materials and Method: This double blind clinical trial study was conducted on 70 menopause women (two 35-person groups) picked out by a purposive sampling procedure. The first group received 160 mg <em>Hypericum Perforatum</em> L. (Perforin pill) while the second one received a placebo (ineffective pill). Menopause symptoms of 2, 4, 6, and 8 weeks after taking the pill or placebo were recorded in the ’Kupperman index’ for menopause symptoms. The gathered data were then analyzed via independent t-test, one-way ANOVA, and repeated measure variance. Significance level was P≤0.05. Results: The age average in the medicine group was 50.49±2.74 and in the placebo group was 50.63±2.87. Body Mass Index (BMI) showed an overweight in both groups (27.29±0.75, 27.23±0.64). Furthermore, comparing the ’Kupperman index’for symptoms between the two groups in 6, 4, and 8 weeks after intervention revealed that the <em>Hypericum Perforatum</em> L. significantly had positive effects on alleviation of eraly menopause symptoms compared to placebo (P≤0.001). Conclusion: The results indicated that <em>Hypericum Perforatum</em> L. might alleviate the severity of early menopause symptoms. Thus, given its being economical and also its slight side effects, it is recommended as a suitable and desirable replacement for counterpart chemical medicine.</p> <p> </p>}, number={2}, journal={International Journal of Ayurvedic Medicine}, author={Tarashoki, Ehsan Bandani and Azizi, Maryam and Pelarak, Ferdos and Kermani, Alieh Etemadi and Madmoli, Yaghoob and Khodadadi, Mahboobe and Najarian, Mahyar}, year={2019}, month={Jul.}, pages={189–193} }