@article{Arjunan_Sah_Rajan_2021, title={Neuroprotective role of Glycyrrhiza glabra on chronic noise induced changes in Hippocampal morphology and its functions in wistar albino rats}, volume={12}, url={https://www.ijam.co.in/index.php/ijam/article/view/1871}, DOI={10.47552/ijam.v12i3.1871}, abstractNote={<p>Background: Noise has become inexorable stress due to the increase in urbanization, automobile usage, and lifestyle modification.Aim: The study aims to investigate the effect of chronic noise stress on hippocampal morphology and the neuroprotective effect of <em>Glycyrrhiza glabra </em>(GG) on stress-induced male Wistar albino rats.  Methods: Adult albino rats were randomly divided into four groups. Each group contained six animals. Rats exposed to chronic noise stress (100 dB/4 h – 30Days),  Noise + GG (150 mg/kg Bw/Oral), and GG alone were compared with control animal and assessed for behaviour using the hole-board test, marble burying test, the morphology of hippocampus by histology, DNA fragmentation and assessed the Phytochemical constitutes in GG. Results: The rats exposed to chronic noise stress showed significance (p<0.05) of behavioral alterations such as increased fear and anxiety, obsessive-compulsive behaviour, enlarged lateral ventricle, and reduced hippocampal volume. Conclusion: The results reported that chronic noise stress affects the neurobehavioral due to reduced hippocampal volume.</p>}, number={2}, journal={International Journal of Ayurvedic Medicine}, author={Arjunan, Archana and Sah, Dhiraj Kumar and Rajan, Ravindran}, year={2021}, month={Jun.}, pages={226–231} }