Anticonvulsant activity of Shankhapuspi (Convolvulus pluricaulis Chois) on Strychnine induced seizure in experimental animals

Authors

  • Kshirod Kumar Ratha Research Officer (Ayurveda), RRIHF,CCRAS, Tarikhet
  • Sthiti Srujani Mishra Dr.Sthiti Srujani Mishra Ayurvedic Medical Officer. Govt.Ayurvedic College& Hospital,Balangir, PO/Dist- Balangir (Odisha),Ph- +918658126826

DOI:

https://doi.org/10.47552/ijam.v3i2.163

Keywords:

Shankhapuspi, Covolvulus pluricaulis, Strychnine, Anticonvulsant activity

Abstract

The anticonvulsant activity of the aqueous extract of Convolvulus pluricaulis Chois (Shankhapuspi) was studied against Strychnine induced convulsions.

Seizure was induced by Strychnine in Shankhapuspi used animal model. The co-administration of the standard anticonvulsant drug Phenytoin sodium and aqueous extract of Shankhapuspi resulted in significant anticonvulsant activity when compared to the anticonvulsive activity of Phenytoin sodium.

The results of the study clearly suggested that Shankhapuspi can be prescribed as a co-therapeutic agent of Phenytoin for arresting seizures induced by Strychnine.

Author Biographies

Kshirod Kumar Ratha, Research Officer (Ayurveda), RRIHF,CCRAS, Tarikhet

SCIENTIST-1,CCRAS,DEPT OF AYUSH,MO H&FW,GOVT OF INDIA

Sthiti Srujani Mishra, Dr.Sthiti Srujani Mishra Ayurvedic Medical Officer. Govt.Ayurvedic College& Hospital,Balangir, PO/Dist- Balangir (Odisha),Ph- +918658126826

Ayurvedic Medical Officer.Govt.Ayurvedic College& Hospital,Balangir, PO/Dist- Balangir (Odisha),Ph- +918658126826

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Published

20-08-2012

How to Cite

Ratha, K. K., & Mishra, S. S. (2012). Anticonvulsant activity of Shankhapuspi (Convolvulus pluricaulis Chois) on Strychnine induced seizure in experimental animals. International Journal of Ayurvedic Medicine, 3(2). https://doi.org/10.47552/ijam.v3i2.163

Issue

Vol. 3 No. 2 (2012): April - June 2012

Section

Research Articles

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