Pre and Post test Clinical study to evaluate the Immunomodulatory effect (IgE) of Virecana followed by Citrakaharitaki Leha in Allergic Asthma

  • Jyotish S Jayandan
  • James Chacko
  • Devipriya Soman
  • Mahesh C Kundagol
Keywords: Allergic Asthma, Ayurveda, Virecana, Citrakaharitaki Leha, Tamaka Svasa

Abstract

Allergic Asthma is one among the diseases which imposes a great burden on the subjects by hampering the quality of life of patients, reducing productivity, and causing work absence. The literary search hinted that there are no published works reporting both clinical and immunological(IgE) outcomes in Allergic Asthma. So the present study was a pre and post test clinical study to evaluate the effect of Ayurvedic line of management in inducing both immunological(IgE) and clinical outcomes in Allergic Asthma. In this study 30 patients were administered classical Virecana Karma (drug induced purgation) followed by Shamanoushadi (internal medicine) for 30 days. Statistical Analysis was done using SPSS VER. 20. Wilcoxon signed rank test was used to evaluate the Subjective parameters, in order to interpret the time of significant change. For objective parameters Paired Samples t- Test was used to evaluate the difference of significant change. The results showed improvement in the subjective criteria, objective criteria and the overall effect of the therapy with the exception of no statistically significant results in immunomodulatory (IgE) effect which proves that the particular management protocol adopted is found to be clinically efficant but not effective in inducing changes at the immune level.

Author Biographies

Jyotish S Jayandan

PG Scholar, Department of Kayachikitsa, School of Ayurveda, Amrita Vishwa Vidyapeetham, Vallikavu, Clappana P.O, Kollam, Kerala, India.

James Chacko

Professor and Head, Department of Kayachikitsa, School of Ayurveda, Amrita Vishwa Vidyapeetham, Vallikavu, Clappana P.O, Kollam, Kerala, India.

Devipriya Soman

Assistant Professor, Department of Kayachikitsa, School of Ayurveda, Amrita Vishwa Vidyapeetham, Vallikavu, Clappana p.o, Kollam, Kerala, India.

Mahesh C Kundagol

Associate Professor, Department of Kayachikitsa, School of Ayurveda, Amrita Vishwa Vidyapeetham, Vallikavu, Clappana P.O, Kollam, Kerala, India.

Published
2021-03-31
How to Cite
Jayandan, J., Chacko, J., Soman, D., & Kundagol, M. (2021). Pre and Post test Clinical study to evaluate the Immunomodulatory effect (IgE) of Virecana followed by Citrakaharitaki Leha in Allergic Asthma. International Journal of Ayurvedic Medicine, 12(1), 53-61. https://doi.org/10.47552/ijam.v12i1.1743
Section
Research Articles