Randomized controlled trial to assess the efficacy and safety of Facia Men’s capsule for hair loss

Abstract

Excessive thinning and losing of hair are prominent symptoms of hair loss, which can significantly lower an individual’s quality of life. This randomized, open label-controlled, clinical trial observed at the effectiveness and safety of Facia Men’s capsule for treating male pattern hair loss.  Facia Men’s capsule includes extracts of Serenoa repens  dry fruits and Cucurbita pepo seeds, vitamins and minerals that help with hair growth and reduce shedding. A total of 126 male participants aged between 18 to 45 years with androgenetic alopecia were evenly split into intervention and control groups. Participants in the treatment group were instructed to take two capsules twice daily over a 12 weeks intervention period. No treatment given for the control group. Effectiveness was measured using daily hair loss counts, shampoo hair counts, hair pull tests while  safety study was monitored 12 weeks utilizing Serum Creatinine, Alanine aminotransferase, Aspartate aminotransferase, and fasting blood sugar. The results showed a significant reduction in hair shedding across all subjective and objective measures in the treatment group compared to the placebo group (p < 0.001). No significant changes appeared in tests for renal and liver function, confirming safety. In terms of average hair fall counts, above 60% improvement has been observed among the treatment group. There was a small but statistically significant change in fasting blood glucose, which suggests the need for future monitoring of metabolic health. These findings indicated that Facia Men’s capsule is an effective and safe herbal option for managing male pattern hair loss.