Preparation, Quality evaluation and Gas Chromatography Mass Spectrometry (GCMS) Analysis of Amalakyadi churna
DOI:
https://doi.org/10.47552/ijam.v17i2.6655Keywords:
Amalakyadi choorna, Appetizer, Bioactive compounds, Flame photometry, Gas chromatography-mass spectrometry, Phytochemical profiling, Quality controlAbstract
Background: Amalakyadi churna (AC) (drug powdered) is a familiar Ayurveda formulation mentioned in classical texts such as Sharangdhara Samhita (Madhyamakhanda, Chapter 6, Shloka 7), Gadanigraha (Part 1, Churna adhikara, Chapter 3, Shloka 372) and Ayurvedic Formulary of India. Systemic studies on AC was limited. In Ayurveda, it is chiefly used for treating fever, ruchikara (appetizer), dipana (digestive stimulant), pachana (carminative), bhedi (breaking) & kapha pacifying effect (phlegm). Aim: To prepare and evaluate quality of Amalakyadi Churna. Objective: To evaluate quality of AC by using GCMS profile. Materials and Methods: Evaluation tested quality, purity of AC using standard tests. Raw ingredients was authenticated and formulation was tested for colour, taste and odour. Physicochemical framework; LOD, acid insoluble ash, total ash and extractive values was determined. Microbial testing suggests safety, while calculate sodium, potassium. Phytochemical test recognizes bioactive compounds and GCMS analysis profiled quantified the chemical phytoconstituents. Results: AC showed proved organoleptic traits, acceptable physicochemical values, safe microbial limits and key minerals. GCMS finds 41 compounds. Phytochemicals (alkaloids, flavonoids, tannins, amino acids and monosaccharides) support its traditional use in jwara, bhedi, appetite improving, digestive aid and kapha pacifier. Conclusion: The bioactive compounds identified from GC MS profiling, which supports its ayurvedic use in stimulating appetite, digestion, jwara, bhedi & kapha pacifier.
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