A Single Blind Clinical Study on Evaluation of effect of Amalaki Choorna and Kulatha Choorna in PCOS

Abstract

Introduction: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting approximately 2.2% to 26% of women worldwide, primarily in the adolescent and reproductive age group (18–45 years). PCOS is a multi factorial condition that impacts reproductive, metabolic, endocrine, and psychological systems. Due to its complex and heterogeneous presentation, comprehensive management remains challenging. In Ayurveda, no single disease entity is directly comparable to PCOS. However, certain clinical manifestations resemble Granthibhoota Artava Dushti, which, if left untreated, may progress to a clinical picture similar to PCOS.Aim To evaluate the effect of Amalaki Choorna and Kulatha Choorna, in patients of PCOS. Materials and Methods: A single-blind, (patient-blinded) Quasi experiment(before & after ) clinical study was conducted on 70 diagnosed PCOS patients. Intervention:Amalaki Choorna – 10 gm daily in divided doses for 90 days Anupana: Honey (Madhu) with warm water (Ushnodaka) Kulatha  yusha (Prepared from choorna) – 10 gm daily in divided doses for 90 days Advised in the form of Yusha (gruel) Outcome Measures: Subjective and objective parameters were assessed, including:Irregularity of menstrual cycle (P = 0.003),Quantity of menstrual blood (P = 0.001), Dysmenorrhea (P = 0.001),Ultrasonographic assessment of ovarian cyst size (P = 0.001). Results:Patients showed statistically highly significant improvement in menstrual regularity, menstrual blood quantity, and pain during menstruation. Ultrasonography demonstrated a significant reduction in ovarian cyst size after treatment. Conclusion: Amalaki Choorna with Madhu and Kulatha Yusha may help to  reduce symptoms of PCOS,Regulate menstruation and ovulation, Improve haemoglobin levels, Modulate hormonal parameters such as LH, FSH,TSH.