An open-label pilot study evaluating the effectiveness of Nava uppu mezhugu (Internal) and Peenisa thailam (External) for the management of Peenisam (Sinusitis)

Authors

  • Lohapriya Lakshmipathy PG Scholar, Department of Maruthuvam, National Institute of Siddha, Chennai – 47, Affiliated to Tamilnadu Dr. M.G.R Medical University, Chennai-32, India.
  • Nalini Sofia H Professor, Department of Maruthuvam, National Institute of Siddha, Chennai – 47, Affiliated to Tamilnadu Dr. M.G.R Medical University, Chennai-32, India.
  • Vetha Merlin Kumari H Professor and Head of the Department, Department of Maruthuvam, National Institute of Siddha, Chennai – 47, Affiliated to Tamilnadu Dr. M.G.R Medical University, Chennai-32, India.
  • Senthilvel G Director (I/C), Professor and Head of the Department, Department of Gunapadam, National Institute of Siddha, Chennai – 47, Affiliated to Tamilnadu Dr. M.G.R Medical University, Chennai-32, India.

DOI:

https://doi.org/10.47552/ijam.v17i2.6982

Keywords:

Peenisam, Sinusitis, Nava Uppu Mezhugu, Peenisa thailam, Siddha medicine, ADSS

Abstract

Background: Peenisam (Sinusitis) is a common nasal disorder described in Siddha literature, primarily due to derangement of kabam (Mucus accumulation). Objective: The study was designed to evaluate the clinical effectiveness of Siddha classic herbo-mineral formulation Nava Uppu Mezhugu (Internal) and Peenisa thailam (External-Oil Bath) for the management of Peenisam (Sinusitis). Methods: The study was conducted in patients diagnosed with Peenisam (Sinusitis) at Ayothidas Pandithar Hospital, National Institute of Siddha (IEC No. NIS/26/IEC/2024/M.P/9, CTRI/2024/06/068796) involving 15 patients within age limit of 18 to 60 years based on inclusion and exclusion criteria. Before starting the trial, Informed consent was obtained from each patient. Internal medicine Nava Uppu Mezhugu was given at a dose of 56 mg with Panai vellam (Palm jaggery), twice a day and External medicine Peenisa Thailam was given to take oil bath weekly once for the period of 28 days. The clinical improvement by using Adelaide Disease Severity Score was documented before and after treatment. The treatment was well tolerated and no adverse drug reaction was found during this trial. Results: Biostatistical report of Adelaide Disease Severity Score (ADSS) before and after treatment were statistically analysed using Wilcoxon Signed Rank Test that showed significant P value of 0.00064. Statistical analysis revealed that there is a significant (p value<0.001) difference before and after treatment. Conclusion: The study has concluded that the interventional drug is therapeutically effective and safe for the management of Peenisam (Sinusitis).

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Published

2026-06-30

How to Cite

Lakshmipathy, L., H, N. S., Kumari H, V. M., & G, S. (2026). An open-label pilot study evaluating the effectiveness of Nava uppu mezhugu (Internal) and Peenisa thailam (External) for the management of Peenisam (Sinusitis). International Journal of Ayurvedic Medicine, 17(2), 411–416. https://doi.org/10.47552/ijam.v17i2.6982

Issue

Vol. 17 No. 2 (2026): April - June 2026

Section

Research Articles

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